Human Gene Mutation David Cooper

ISBN: 9780122204395

Published: January 1st 1993

Unknown Binding

412 pages


Description

Human Gene Mutation  by  David Cooper

Human Gene Mutation by David Cooper
January 1st 1993 | Unknown Binding | PDF, EPUB, FB2, DjVu, talking book, mp3, RTF | 412 pages | ISBN: 9780122204395 | 6.75 Mb

Enormous progress has recently been made in the analysis and diagnosis of human inherited disease and in the characterization of the underlying genes and their associated pathological lesions. Human Gene Mutation brings together for the first time aMoreEnormous progress has recently been made in the analysis and diagnosis of human inherited disease and in the characterization of the underlying genes and their associated pathological lesions. Human Gene Mutation brings together for the first time a short history of mutation research, a comprehensive analysis of the nature of human gene mutation (single base-pair substitutions, deletions, splice site, promoter mutations, etc.), and an assessment of the consequences of mutation at the level of gene expression and for the complex relationship between genotype and clinical phenotype.

Laboratory methods for mutation detection and analysis of current possibilities in molecular diagnostic medicine are also reviewed. The central theme of this volume is the nonrandomness of human gene mutation and its implications for both the nature and the prevalence of genetic disease.

The awareness that certain DNA sequences are hypermutable provides vital new clues as to the basic (and endogenous) mechanisms of mutagenesis. Novel explanatory and predictive models of mutagenesis are proposed. Together this constitutes a unique approach to understanding the ultimate causes of human genome pathology.

This volume in the Human Molecular Genetics series is an important companion for all human molecular geneticists and genetic counselors as well as interested clinicians and postgraduates.



Enter the sum





Related Archive Books

  1. 16.05.2013Bottlenose Dolphin
  2. 23.04.2011Alef
  3. 18.08.2011Die Blaue Eislilie
  4. 28.02.2012Die Marshals: Snake Snider


Related Books


Comments

Comments for "Human Gene Mutation":


arkangelshakespeare.com

©2011-2015 | DMCA | Contact us